For what it’s worth:
“In 1736 I lost one of my sons, a fine boy of four years old, by the small-pox, taken in the common way. I long regretted bitterly, and still regret that I had not given it to him by inoculation.
This I mention for the sake of parents who omit that operation, on the supposition that they should never forgive themselves if a child died under it; my example showing that the regret may be the same either way, and that, therefore, the safer should be chosen.”
Ben Franklin
I think you're missing the point here. Would he be in favor of limiting free speech or shutting down the country after an effective vaccine was available? No.
There's nothing wrong with promoting the importance of vaccination, as many republicans have done. The problem is when you start impeding on people's liberties and free will.